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Nazzareno Galiè Selected Research

Endothelin Receptor Antagonists

1/2019Evaluation of Macitentan in Patients With Eisenmenger Syndrome.
1/2017Macitentan Improves Health-Related Quality of Life for Patients With Pulmonary Arterial Hypertension: Results From the Randomized Controlled SERAPHIN Trial.
1/2017SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension.
12/2015Selexipag for the Treatment of Pulmonary Arterial Hypertension.
5/2015Riociguat for the treatment of pulmonary arterial hypertension: a long-term extension study (PATENT-2).
1/2015Effect of macitentan on hospitalizations: results from the SERAPHIN trial.
8/2013Macitentan and morbidity and mortality in pulmonary arterial hypertension.
7/2013Riociguat for the treatment of pulmonary arterial hypertension.
12/2012Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): a randomized controlled trial.
6/2009Tadalafil therapy for pulmonary arterial hypertension.
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Nazzareno Galiè Research Topics

Disease

68Pulmonary Arterial Hypertension
01/2022 - 05/2002
15Pulmonary Hypertension
03/2022 - 08/2002
11Connective Tissue Diseases (Connective Tissue Disease)
02/2018 - 11/2005
8Disease Progression
01/2022 - 11/2004
8Familial Primary Pulmonary Hypertension
01/2019 - 05/2002
7Dyspnea (Shortness of Breath)
10/2014 - 08/2002
6Headache (Headaches)
10/2021 - 10/2008
6Congenital Heart Defects (Congenital Heart Defect)
01/2019 - 10/2008
5Hemorrhage
11/2021 - 09/2006
5Pulmonary Embolism
09/2021 - 12/2013
4Pain (Aches)
10/2020 - 05/2002
3Heart Failure
01/2022 - 06/2009
3Nausea
10/2021 - 10/2008
3Diarrhea
10/2021 - 11/2005
3Vascular Diseases (Vascular Disease)
10/2021 - 01/2003
3Myocardial Infarction
01/2021 - 01/2019
3MINOCA
01/2021 - 01/2019
3Thrombosis (Thrombus)
11/2020 - 01/2020
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2020 - 01/2019
3Eisenmenger Complex (Eisenmenger's Syndrome)
01/2019 - 07/2006
3Portal Hypertension
06/2012 - 01/2003
3HIV Infections (HIV Infection)
06/2012 - 01/2003
2Neoplasms (Cancer)
11/2020 - 01/2020
2Aortic Valve Stenosis (Aortic Stenosis)
10/2020 - 05/2014
2Stroke (Strokes)
10/2020 - 04/2014
2Hypertension (High Blood Pressure)
10/2019 - 04/2017
2Respiratory Tract Infections (Respiratory Tract Infection)
01/2019 - 06/2009
2Hypoxia (Hypoxemia)
06/2009 - 06/2004
2Flushing
06/2009 - 11/2005
2Dyspepsia (Indigestion)
10/2008 - 11/2005
2Hypothermia
07/2008 - 09/2006
2Clinical Deterioration
01/2007 - 08/2002
1Infections
02/2022
1Ventricular Tachycardia
01/2022
1Ventricular Remodeling
01/2022
1Fabry Disease (Fabry's Disease)
12/2021
1Acute Coronary Syndrome
11/2021
1Cardiovascular Diseases (Cardiovascular Disease)
10/2021
1Amyloidosis
10/2021
1Sudden Death
10/2021
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
10/2021
1Aortic Valve Insufficiency (Aortic Regurgitation)
10/2021
1Hyperglycemia
01/2021
1Cardiac Arrhythmias (Arrythmia)
12/2020

Drug/Important Bio-Agent (IBA)

15Endothelin Receptor AntagonistsIBA
01/2019 - 04/2003
13Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2021 - 05/2002
12selexipagIBA
01/2022 - 10/2012
11Bosentan (Tracleer)FDA Link
11/2016 - 04/2003
10macitentanIBA
01/2022 - 08/2013
10Tadalafil (Cialis)FDA Link
10/2021 - 06/2009
9Sildenafil Citrate (Viagra)FDA Link
08/2015 - 11/2005
7Pharmaceutical PreparationsIBA
10/2021 - 06/2004
6Epoprostenol ReceptorsIBA
01/2022 - 10/2012
6ambrisentanFDA Link
12/2019 - 06/2008
6riociguatIBA
05/2017 - 07/2013
6ProstaglandinsIBA
05/2015 - 01/2003
5AnticoagulantsIBA
09/2021 - 11/2002
5Brain Natriuretic Peptide (Natrecor)FDA Link
01/2021 - 06/2008
4Endothelins (Endothelin)IBA
01/2019 - 07/2006
4Phosphodiesterase 5 InhibitorsIBA
12/2015 - 09/2006
4Oxygen (Dioxygen)IBA
06/2009 - 11/2002
4DiureticsIBA
06/2009 - 11/2002
3Biomarkers (Surrogate Marker)IBA
12/2021 - 11/2004
3Heparin (Liquaemin)FDA LinkGeneric
09/2021 - 04/2014
3Glucose (Dextrose)FDA LinkGeneric
01/2021 - 10/2019
3pro-brain natriuretic peptide (1-76)IBA
01/2019 - 07/2013
3Soluble Guanylyl CyclaseIBA
01/2016 - 07/2013
22'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
11/2021 - 01/2019
2DabigatranFDA Link
09/2021 - 12/2017
2Troponin IIBA
01/2021 - 04/2014
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
11/2020 - 05/2020
2Biological ProductsIBA
10/2020 - 01/2019
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2019 - 06/2009
2TenecteplaseFDA Link
03/2017 - 04/2014
2Vasodilator Agents (Vasodilators)IBA
01/2016 - 01/2007
2Carbon MonoxideIBA
10/2014 - 12/2013
2treprostinilFDA Link
12/2012 - 01/2003
2Digoxin (Digitek)FDA LinkGeneric
06/2009 - 11/2002
2Calcium Channel Blockers (Blockers, Calcium Channel)IBA
06/2009 - 11/2002
2Iloprost (Ventavis)FDA Link
01/2003 - 08/2002
1Anti-Bacterial Agents (Antibiotics)IBA
02/2022
1Guanidine (Guanidine Nitrate)FDA Link
01/2022
1Prealbumin (Transthyretin)IBA
10/2021
1tafamidisIBA
10/2021
1Proteins (Proteins, Gene)FDA Link
10/2021
13-Iodobenzylguanidine (Iobenguane)IBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2021
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
12/2020

Therapy/Procedure

42Therapeutics
03/2022 - 08/2002
9Endarterectomy (Thromboendarterectomy)
03/2022 - 09/2006
6Lung Transplantation
01/2016 - 09/2006
2Transcatheter Aortic Valve Replacement
10/2021 - 05/2014
2Percutaneous Coronary Intervention
01/2020 - 11/2017
2Stents
01/2020 - 01/2020
1Antibiotic Prophylaxis
02/2022
1Enzyme Replacement Therapy
12/2021
1Drug-Eluting Stents
11/2021
1Drug Therapy (Chemotherapy)
10/2021
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
10/2021